CONSIDERATIONS TO KNOW ABOUT NEMBUTAL DRUG

Induction of microsomal enzymes by this drug, might shorten the 50 %-lifetime of doxycycline for as long as two weeks right after barbiturate therapy discontinued; monitor clinical reaction to doxycycline intently if both equally drugs administered concurrentlypentobarbital boosts effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism.